![]() Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general or local perfusion, or inability of the affected tissues to extract oxygen from, or metabolically process, an adequate supply of oxygen from an adequately oxygenated blood supply. Hypoxia in which there is complete absence of oxygen supply is referred to as anoxia. Hypoxia differs from hypoxemia and anoxemia, in that hypoxia refers to a state in which oxygen present in a tissue or the whole body is insufficient, whereas hypoxemia and anoxemia refer specifically to states that have low or no oxygen in the blood. ![]() Although hypoxia is often a pathological condition, variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxiation, lack of oxygen, low blood oxygen (technically hypoxemia), oxygen starvationĬyanosis of the hand in an elderly person with low oxygen saturationĬyanosis, numbness or pins and needles feeling of the extremitiesÄiabetes, coronary artery disease, heart attack, stroke, embolism, thrombosis, deep-vein thrombosis, tobacco smoking
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